Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957847 | 0.94 | GRIN1 (0.36) | EGFRKCNH3GRM5LMNATP53 | |
| SCHEMBL6969559 | 0.88 | MEN1 (0.37) | DHFRLMNATP53KMT2A | |
| SCHEMBL6963615 | 0.87 | KMT2A (0.35) | EGFRLMNATP53KMT2A | |
| SCHEMBL6970019 | 0.86 | SMN1; SMN2 (0.37) | EGFRKCNH3LMNATP53KMT2A | |
| SCHEMBL6960659 | 0.85 | POLB (0.38) | EGFRKCNH3LMNAKMT2APARP1 | |
| SCHEMBL6966508 | 0.85 | KMT2A (0.37) | EGFRKCNH3TP53KMT2ACDK2 | |
| SCHEMBL6962677 | 0.85 | SLC2A1 (0.40) | EGFRKCNH3KMT2APARP1CDK2 | |
| Hydrochloric Acid SCHEMBL6966805 | 0.85 | MC4R (0.34) | KCNH3DHFRLMNATP53KMT2A | |
| Hydrochloric Acid SCHEMBL6966802 | 0.85 | MC4R (0.34) | KCNH3DHFRLMNATP53KMT2A | |
| SCHEMBL6955926 | 0.85 | P2RX3 (0.34) | EGFRLMNATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |