Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453905 | 0.91 | MAPT (0.79) | ALDH1A1GAAMAPTCYP3A4KMT2A | |
| SCHEMBL6959673 | 0.87 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTKMT2AHTT | |
| SCHEMBL6955653 | 0.87 | MAPT (0.61) | ALDH1A1GAAMAPTKMT2AHTT | |
| SCHEMBL6965795 | 0.84 | KMT2A (0.64) | ALDH1A1GAAMAPTKMT2ANPSR1 | |
| SCHEMBL23264324 | 0.83 | ALDH1A1 (0.68) | ALDH1A1GAAMAPTKMT2AHTT | |
| SCHEMBL28109166 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTCYP3A4TAS2R38 | |
| SCHEMBL5452442 | 0.82 | MAPT (0.72) | ALDH1A1GAAMAPTCYP3A4KMT2A | |
| SCHEMBL10909195 | 0.82 | ALDH1A1 (0.66) | ALDH1A1GAAMAPTKMT2AHTT | |
| SCHEMBL6958883 | 0.81 | KMT2A (0.66) | ALDH1A1GAAMAPTKMT2AHTT | |
| SCHEMBL16041474 | 0.81 | MAPT (1.00) | ALDH1A1GAAMAPTCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |