Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955646 | 0.87 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAL3MBTL1KMT2A | |
| SCHEMBL9453905 | 0.85 | MAPT (0.79) | ALDH1A1MAPTGAAL3MBTL1KMT2A | |
| SCHEMBL6955653 | 0.82 | MAPT (0.61) | ALDH1A1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6961905 | 0.80 | GAA (0.62) | ALDH1A1MAPTGAAL3MBTL1KDM4E | |
| SCHEMBL6952759 | 0.78 | NPSR1 (0.67) | ALDH1A1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL23264324 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAL3MBTL1KDM4E | |
| SCHEMBL7082828 | 0.77 | GAA (0.55) | ALDH1A1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL10570399 | 0.77 | PTGS1 (0.54) | ALDH1A1GAASMN1; SMN2KMT2APOLB | |
| SCHEMBL5452442 | 0.77 | MAPT (0.72) | ALDH1A1MAPTGAAL3MBTL1KMT2A | |
| SCHEMBL6958883 | 0.76 | KMT2A (0.66) | ALDH1A1MAPTGAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |