Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955653 | 0.84 | MAPT (0.61) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL6955646 | 0.84 | ALDH1A1 (0.68) | KMT2AALDH1A1MAPTNPSR1GAA | |
| SCHEMBL9453905 | 0.82 | MAPT (0.79) | KMT2AALDH1A1MAPTALOX12NPSR1 | |
| SCHEMBL16566574 | 0.81 | ALDH1A1 (0.65) | KMT2AALDH1A1MAPTMEN1ALOX12 | |
| SCHEMBL16566486 | 0.81 | ALDH1A1 (0.69) | KMT2AALDH1A1MAPTMEN1ALOX12 | |
| SCHEMBL29481122 | 0.80 | IDO1 (0.79) | KMT2AALDH1A1MAPTMEN1GAA | |
| SCHEMBL26991 | 0.80 | IDO1 (0.79) | KMT2AALDH1A1MAPTMEN1GAA | |
| SCHEMBL6958883 | 0.79 | KMT2A (0.66) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL3054417 | 0.79 | NPC1 (0.60) | ALDH1A1 | |
| SCHEMBL5454961 | 0.78 | MAOB (0.75) | KMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |