Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950423 | 0.87 | TBXAS1 (0.56) | TBXAS1PKMSMN1; SMN2TP53MAPK1 | |
| SCHEMBL1509582 | 0.84 | TBXAS1 (0.53) | TBXAS1CYP19A1PKMSMN1; SMN2EGLN3 | |
| SCHEMBL6964199 | 0.76 | CXCR2 (0.42) | TBXAS1PTGDR2 | |
| SCHEMBL6958299 | 0.76 | CYP19A1 (0.46) | TBXAS1CYP19A1 | |
| SCHEMBL14027515 | 0.72 | TBXAS1 (0.54) | TBXAS1CYP19A1 | |
| SCHEMBL11287283 | 0.72 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL6948774 | 0.72 | POLB (0.60) | TBXAS1CYP19A1EGLN3POLB | |
| Hydrochloric Acid SCHEMBL7970769 | 0.72 | TBXAS1 (0.42) | TBXAS1CYP19A1PKMSMN1; SMN2KMT2A | |
| SCHEMBL6955408 | 0.71 | CYP19A1 (0.47) | TBXAS1CYP19A1 | |
| SCHEMBL6955399 | 0.71 | CYP19A1 (0.47) | TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974584-B1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6420375-B1 | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |