SCHEMBL69557

SCHEMBL69557

O=C1CCSc2ccc(C(F)(F)F)cc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.58
ELOC Q15369 1/20 0.58
ELOB Q15370 1/20 0.58
CTSL P07711 1/20 0.51
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
PARP1 P09874 2/20 0.43
PARP10 Q53GL7 1/20 0.43
HTT P42858 1/20 0.43
PTPN5 P54829 1/20 0.41
ATM Q13315 2/20 0.39
TDP2 O95551 1/20 0.36
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
PARP2 Q9UGN5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3592594 0.88 KDM4E (0.55) VHLELOCELOBCTSLKDM4E
SCHEMBL9607631 0.83 VHL (0.58) VHLELOCELOBCTSLKDM4E
SCHEMBL69406 0.83 PTPN5 (0.43) VHLELOCELOBCTSLALDH1A1
SCHEMBL12743 0.77 VHL (0.64) VHLELOCELOBCTSLKDM4E
SCHEMBL29595944 0.77 VHL (0.64) VHLELOCELOBCTSLKDM4E
SCHEMBL24460532 0.76 PARP1 (0.57) CTSLPARP1PARP10PTPN5TDP2
SCHEMBL69544 0.74 VHL (1.00) VHLELOCELOBCTSLKDM4E
SCHEMBL6592045 0.74 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69249 0.74 VHL (0.64) VHLELOCELOBCTSLKDM4E
SCHEMBL69545 0.74 VHL (0.64) VHLELOCELOBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
EP-3689981-B1 ACTINIC-RAY-CURABLE INK-JET INK, LIGHT-SHIELDING FILM, AND PRODUCTION METHOD FOR LIGHT-SHIELDING FILM FUJIFILM CORP (JP) 2024-07-10 EP disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
EP-3950856-A1 PHOTOCURABLE INK COMPOSITION AND METHOD FOR IMAGE RECORDING FUJIFILM Corporation (JP) 2022-02-09 EP disclosed
US-20210395549-A1 PHOTOCURABLE INK COMPOSITION AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
US-20200199385-A1 ACTIVE ENERGY RAY CURABLE-TYPE INK JET INK, LIGHT SHIELDING FILM, AND METHOD OF MANUFACTURING LIGHT SHIELDING FILM FUJIFILM CORPORATION (JP) 2020-06-25 US disclosed
EP-2412768-B1 Inkjet ink composition, inkjet recording method, and printed material FUJIFILM CORP (JP) 2019-01-23 EP disclosed
US-9878560-B2 Inkjet recording method using nozzle arrays and printed material obtained by the inkjet recording method FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
EP-2345703-B1 Inkjet ink composition and inkjet recording method FUJIFILM CORP (JP) 2017-09-13 EP disclosed
EP-2192163-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2017-04-19 EP disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-1975210-A1 Ink set for inkjet recording and inkjet recording method FUJIFILM Corporation (JP) 2008-10-01 EP disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed
EP-0212428-B1 DIHYDROBENZO/B /THIOPHENES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS ANTIFUNGALS SCHERING CORPORATION (US) 1990-06-06 EP disclosed
US-4731364-A Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1988-03-15 US disclosed
EP-0212428-A1 Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1987-03-04 EP disclosed