SCHEMBL69249

SCHEMBL69249

O=C1CCSc2ccc(Br)cc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.64
ELOC Q15369 1/20 0.64
ELOB Q15370 1/20 0.64
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CTSL P07711 1/20 0.48
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
S100A4 P26447 1/20 0.41
PARP10 Q53GL7 2/20 0.39
PARP1 P09874 1/20 0.39
PTPRC P08575 1/20 0.36
METAP1 P53582 1/20 0.36
CA2 P00918 3/20 0.36
PBRM1 Q86U86 1/20 0.36
BCL2 P10415 1/20 0.35
MCL1 Q07820 1/20 0.35
CA1 P00915 1/20 0.35
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL8101571 0.96 VHL (0.60) VHLELOCELOBKDM4EALDH1A1
SCHEMBL5203764 0.89 VHL (0.51) VHLELOCELOBKDM4EALDH1A1
SCHEMBL13135 0.85 KDM4E (0.58) VHLELOCELOBKDM4EALDH1A1
SCHEMBL30714352 0.85 KDM4E (0.58) VHLELOCELOBKDM4EALDH1A1
SCHEMBL7992397 0.82 KDM4E (0.48) VHLELOCELOBKDM4EALDH1A1
SCHEMBL6592045 0.81 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL30829218 0.81 S100A4 (0.43) VHLELOCELOBCTSLTDP1
SCHEMBL5329304 0.81 S100A4 (0.43) VHLELOCELOBCTSLTDP1
SCHEMBL12743 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69544 0.78 VHL (1.00) VHLELOCELOBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
US-20260001886-A1 ENPP1 INHIBITORS I RE VENTURES I LLC (US) 2026-01-01 US disclosed
WO-2025233863-A1 ENPP1 INHIBITORS RE VENTURES I, LLC (US) 2025-11-13 WO disclosed
WO-2025136671-A1 ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
EP-4540230-A1 ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF Ensem Therapeutics, Inc. (US) 2025-04-23 EP disclosed
CN-119136619-A Perovskite solar cell and chemical induction surface reconstruction preparation method 陕西师范大学 2024-12-13 CN disclosed
US-20240246950-A1 Anilino-Pyrazole Derivatives, Compositions and Methods Thereof Ensem Therapeutics (US) 2024-07-25 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
EP-3689981-B1 ACTINIC-RAY-CURABLE INK-JET INK, LIGHT-SHIELDING FILM, AND PRODUCTION METHOD FOR LIGHT-SHIELDING FILM FUJIFILM CORP (JP) 2024-07-10 EP disclosed
EP-0836600-A1 HERBICIDAL KETALS AND SPIROCYCLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-22 EP disclosed
US-5728846-A RETENOIDS, RETINOID ACTIVITY; AGONISTS, ANTAGONISTS ALLERGAN (US) 1998-03-17 US disclosed
WO-1997009297-A2 SYNTHESIS AND USE OF RETINOID COMPOUNDS HAVING NEGATIVE HORMONE AND/OR ANTAGONIST ACTIVITIES VISION PHARMACEUTICALS L.P. (US) 1997-03-13 WO disclosed
WO-1997001550-A1 HERBICIDAL KETALS AND SPIROCYCLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO disclosed
US-4282229-A FOR DIABETIC COMPLICATIONS PFIZER INC. (US) 1981-08-04 US disclosed
US-4258054-A ANTIDIABETIC PFIZER INC. (US) 1981-03-24 US disclosed
US-4210756-A Tetrahydroquinoline hydantoins for chronic diabetic complications PFIZER INC. (US) 1980-07-01 US disclosed
US-4209630-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1980-06-24 US disclosed
US-4147795-A ENZYME INHIBITORS PFIZER INC. (US) 1979-04-03 US disclosed
US-4117230-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1978-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001886-A1 ENPP1 INHIBITORS I ENPP1, ENPP2, ENPP3 VHL 1464/4885ELOC 414/4885ELOB 648/4885
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 VHL 1856/4885ELOC 2247/4885ELOB 3976/4885
US-20240246950-A1 Anilino-Pyrazole Derivatives, Compositions and Methods Thereof CDK2, CDK3, CDK4 VHL 675/4885ELOC 1429/4885ELOB 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.