SCHEMBL69544

SCHEMBL69544

O=C1CCSc2ccc(Cl)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 1.00
ELOC Q15369 1/20 1.00
ELOB Q15370 1/20 1.00
KDM4E B2RXH2 4/20 0.49
ALDH1A1 P00352 4/20 0.49
CTSL P07711 1/20 0.48
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 3/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPSR1 Q6W5P4 1/20 0.43
S100A4 P26447 1/20 0.41
MMP12 P39900 1/20 0.39
F7 P08709 1/20 0.39
PARP1 P09874 1/20 0.39
F3 P13726 1/20 0.39
PARP10 Q53GL7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5114791 0.85 VHL (0.74) VHLELOCELOBKDM4EALDH1A1
SCHEMBL68898 0.81 VHL (0.68) VHLELOCELOBKDM4EALDH1A1
SCHEMBL12743 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69249 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL29595944 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL6592045 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69545 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL10720643 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL56657 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL10364205 0.77 VHL (0.62) VHLELOCELOBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284892-A Stimulus-responsive hyaluronic acid film with adjustable afterglow color 天津大学浙江绍兴研究院 2023-06-23 CN claimed
CN-110698456-B Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof 重庆医药高等专科学校 2021-05-14 CN claimed
CN-102086212-A Antifungal agent-2, 3,4, 5-tetrahydro-4H-benzo [ b ] thiopyrano [4,3-c ] pyrazole-2-carboxamide derivatives UNIV SHENYANG PHARMACEUTICAL 2011-06-08 CN claimed
CN-114031603-B Thiochroman 4-ketone compound, preparation method thereof and UV (ultraviolet) photocuring combination system thereof 深圳市大衍创新材料科技有限公司 2024-07-19 CN disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
WO-2024140431-A1 COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF IONGEN THERAPEUTICS CO., LTD. (CN) 2024-07-04 WO disclosed
CN-116284892-A Stimulus-responsive hyaluronic acid film with adjustable afterglow color 天津大学浙江绍兴研究院 2023-06-23 CN disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
WO-2023026884-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID STATE IMAGE SENSOR, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR 富士フイルム株式会社 2023-03-02 WO disclosed
CN-114031603-A Thiochromane 4-ketone compound, preparation method thereof and UV (ultraviolet) photocuring combination system thereof 深圳市芯研材料科技有限公司 2022-02-11 CN disclosed
US-4228177-A ANTIFUNGAL AND ANTIBACTERIAL AGENTS E. R. SQUIBB & SONS, INC. (US) 1980-10-14 US disclosed
US-4210756-A Tetrahydroquinoline hydantoins for chronic diabetic complications PFIZER INC. (US) 1980-07-01 US disclosed
US-4210663-A ALDOSE REDUCTASE INHIBITORS; TREATMENT OF DIABETIC CATARACTS, NEUROPATHY OR RETINOPATHY PFIZER INC. (US) 1980-07-01 US disclosed
US-4209630-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1980-06-24 US disclosed
EP-0011426-A1 Halogen-substituted benzopyran- and benzothiopyran-4-carboxylic acids, their preparation and pharmaceutical compositions containing the same PFIZER INC. (US) 1980-05-28 EP disclosed
US-4147795-A ENZYME INHIBITORS PFIZER INC. (US) 1979-04-03 US disclosed
US-4117230-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1978-09-26 US disclosed
US-4105778-A ANTIALLERGENS, BACTERICIDES, FUNGICIDES AYERST, MCKENNA & HARRISON, LTD. (CA) 1978-08-08 US disclosed
US-4060619-A ANTIALLERGY, MICROBIOCIDE AYERST MCKENNA AND HARRISON LTD. (CA) 1977-11-29 US disclosed