Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.64 |
| ▸ | ELOC | Q15369 | 1/20 | 0.64 |
| ▸ | ELOB | Q15370 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595944 | 1.00 | VHL (0.64) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL5118761 | 0.89 | VHL (0.51) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL2223179 | 0.85 | KDM4E (0.58) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL4152484 | 0.81 | NOTUM (0.49) | VHLELOCELOBALDH1A1CTSL | |
| SCHEMBL21038005 | 0.78 | VHL (0.51) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL69544 | 0.78 | VHL (1.00) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL6592045 | 0.78 | VHL (0.64) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL69249 | 0.78 | VHL (0.64) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL10720643 | 0.78 | VHL (0.64) | VHLELOCELOBALDH1A1KDM4E | |
| SCHEMBL13349612 | 0.78 | CTSL (0.48) | VHLELOCELOBALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698456-A | Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof | 重庆医药高等专科学校 | 2020-01-17 | — | — | CN | claimed |
| CN-102086212-A | Antifungal agent-2, 3,4, 5-tetrahydro-4H-benzo [ b ] thiopyrano [4,3-c ] pyrazole-2-carboxamide derivatives | UNIV SHENYANG PHARMACEUTICAL | 2011-06-08 | — | — | CN | claimed |
| US-20090197167-A1 | Fluorinated Additives For Lithium Ion Batteries | SOLVAY FLUOR GMBH (DE) | 2009-08-06 | — | — | US | claimed |
| US-10106492-B2 | Fluorinated carbonyl compounds comprising a triple bond, methods for their manufacture and uses thereof | SOLVAY SA (BE) | 2018-10-23 | — | — | US | disclosed |
| US-9969673-B2 | Process for the manufacture of 1, 1′-difluorosubstituted dialkyl carbonates, isomers thereof and electrolyte compositions containing them | SOLVAY S.A. (BE) | 2018-05-15 | — | — | US | disclosed |
| CN-104080780-B | Derivative, its preparation method and its purposes as solvent additive of the meldrum's acid of fluorination | 索尔维公司 | 2018-04-13 | — | — | CN | disclosed |
| EP-2788313-B1 | PROCESS FOR THE MANUFACTURE OF 1,1'-DIFLUOROSUBSTITUTED DIALKYL CARBONATES | SOLVAY (BE) | 2018-02-21 | — | — | EP | disclosed |
| US-9882198-B2 | High performance lithium battery electrodes by self-assembly processing | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-01-30 | — | — | US | disclosed |
| US-9825331-B2 | Fluorinated derivatives of meldrum's acid, a method for the preparation of the same, and their use as a solvent additive | SOLVAY SA (BE) | 2017-11-21 | — | — | US | disclosed |
| CN-104428941-B | The carbonyls of fluorination comprising three keys, its manufacture method and application thereof | 索尔维公司 | 2017-10-13 | — | — | CN | disclosed |
| EP-2785703-B1 | 5-Fluorinated derivatives of Meldrum's acid (5-fluoro-1,3-dioxane-4,6-dione derivatives), methods for their preparation and their use as solvent additives in lithium ion batteries. | SOLVAY (BE) | 2017-01-11 | — | — | EP | disclosed |
| US-4431816-A | FUNGICIDES; BACTERICIDES | SCHERING CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| US-4282229-A | FOR DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4258054-A | ANTIDIABETIC | PFIZER INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4210756-A | Tetrahydroquinoline hydantoins for chronic diabetic complications | PFIZER INC. (US) | 1980-07-01 | — | — | US | disclosed |
| US-4209630-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1980-06-24 | — | — | US | disclosed |
| US-4177282-A | ANITDIABETIC | PFIZER INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4147795-A | ENZYME INHIBITORS | PFIZER INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4130714-A | SPIRO CHROMANS OR THIOCHROMANS | PFIZER INC. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4117230-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1978-09-26 | — | — | US | disclosed |