Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846019 | 0.79 | TNF (0.33) | TNFCRBN | |
| SCHEMBL6957293 | 0.76 | — | — | |
| SCHEMBL7567498 | 0.75 | F2 (0.43) | TNFCRBN | |
| SCHEMBL10670259 | 0.75 | CASP3 (0.43) | — | |
| SCHEMBL10338047 | 0.71 | KDM4E (0.41) | TNFCRBN | |
| SCHEMBL18535556 | 0.71 | ALDH1A1 (0.31) | TNFCRBN | |
| SCHEMBL9294843 | 0.69 | TNF (0.36) | TNFCRBN | |
| SCHEMBL23027211 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL25013367 | 0.69 | — | — | |
| SCHEMBL6954377 | 0.68 | HDAC4 (0.46) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898562-B1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | UPJOHN CO (US) | 2003-01-22 | — | — | EP | claimed |
| CN-1210517-A | Hydroxamic acid derivatives for use with treatment of diseases related to connective tissue degradation | UPJOHN CO (US) | 1999-03-10 | — | — | CN | claimed |
| US-5712300-A | ENZYME INHIBITOR | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-27 | — | — | US | claimed |
| EP-0898562-B1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | UPJOHN CO (US) | 2003-01-22 | — | — | EP | disclosed |
| CN-1210517-A | Hydroxamic acid derivatives for use with treatment of diseases related to connective tissue degradation | UPJOHN CO (US) | 1999-03-10 | — | — | CN | disclosed |
| EP-0898562-A1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5712300-A | ENZYME INHIBITOR | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1997032846-A1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |