Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947461 | 0.89 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| Cyclopropane SCHEMBL6952259 | 0.88 | HTR3E (0.34) | MTNR1A | |
| SCHEMBL6953416 | 0.86 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL6950797 | 0.85 | MTNR1A (0.37) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL6950112 | 0.79 | HTR2A (0.40) | — | |
| SCHEMBL6950109 | 0.78 | PARP1 (0.40) | — | |
| SCHEMBL6945053 | 0.77 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL6953856 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL6951713 | 0.75 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL6944965 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |