Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955883 | 0.88 | MTNR1A (0.43) | MTNR1A | |
| SCHEMBL6950797 | 0.85 | MTNR1A (0.37) | SMN1; SMN2MTNR1AHPGDKMT2A | |
| SCHEMBL6950112 | 0.79 | HTR2A (0.40) | EEDHTR2AHTR2CHTR2BPARP1 | |
| SCHEMBL6950109 | 0.78 | PARP1 (0.40) | HTR3EHTR3BHTR3AHTR4HTR3D | |
| Cyclopropane SCHEMBL6948950 | 0.77 | MTNR1A (0.39) | MTNR1A | |
| SCHEMBL6947461 | 0.77 | MTNR1A (0.45) | MTNR1A | |
| Cyclopropane SCHEMBL6947276 | 0.75 | EED (0.41) | EEDMTNR1A | |
| SCHEMBL6953416 | 0.74 | MTNR1A (0.43) | MTNR1A | |
| Cyclopropane SCHEMBL6956599 | 0.72 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL27376952 | 0.66 | EED (0.32) | EEDHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | claimed |