Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383562 | 1.00 | GLO1 (0.49) | GLO1MAPTAKR1C2PTGS1GAA | |
| SCHEMBL6954032 | 0.84 | MAPT (0.49) | GLO1MAPTGAATDP1HPGD | |
| SCHEMBL31634795 | 0.84 | MAPT (0.49) | GLO1MAPTGAATDP1HPGD | |
| SCHEMBL6954037 | 0.84 | MAPT (0.49) | GLO1MAPTGAATDP1HPGD | |
| SCHEMBL15026456 | 0.84 | MAPT (0.45) | GLO1MAPTAKR1C2PTGS1GAA | |
| SCHEMBL16285261 | 0.84 | GLO1 (0.65) | GLO1MAPTPTGS1HPGD | |
| SCHEMBL10755317 | 0.82 | MEN1 (0.54) | MAPTGAATDP1HPGD | |
| SCHEMBL6960584 | 0.82 | GLO1 (0.46) | GLO1MAPTGAATDP1HPGD | |
| SCHEMBL6960592 | 0.82 | GLO1 (0.46) | GLO1MAPTGAATDP1HPGD | |
| SCHEMBL10353152 | 0.82 | MEN1 (0.54) | MAPTGAATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6482841-B1 | Pyridyl compounds and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2002-11-19 | — | — | US | disclosed |
| EP-1023267-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019302-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 1999-04-22 | — | — | WO | disclosed |
| US-4707486-A | Diaryl piperidine containing esters of 1,4-dihydropyridines and coronary therapeutic use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-11-17 | — | — | US | disclosed |