Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965277 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ACYP1A2MAPTPOLB | |
| SCHEMBL6962164 | 0.84 | MAPT (0.35) | SMN1; SMN2RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL8699464 | 0.82 | MAPT (0.37) | SMN1; SMN2RAB9AMAPTPOLBNPC1 | |
| SCHEMBL6965451 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6960444 | 0.79 | GAA (0.44) | SMN1; SMN2RAB9AMAPTPOLBNPC1 | |
| SCHEMBL6960156 | 0.78 | ALDH1A1 (0.32) | SMN1; SMN2RAB9AMAPTPOLBGAA | |
| SCHEMBL6956204 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6956523 | 0.77 | RAB9A (0.40) | SMN1; SMN2RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6561301 | 0.75 | KMT2A (0.36) | SMN1; SMN2RAB9ACYP1A2CYP2C9CYP2C19 | |
| Benzene SCHEMBL27466605 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ACYP1A2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |