Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335656 | 0.82 | LOXL2 (0.35) | CYP2A6LOXL2 | |
| SCHEMBL16959461 | 0.79 | MEN1 (0.38) | CYP2A6LOXL2MEN1KMT2A | |
| SCHEMBL28049287 | 0.78 | GRM5 (0.31) | CYP2A6LOXL2 | |
| SCHEMBL28302773 | 0.78 | LOXL2 (0.50) | CYP2A6LOXL2 | |
| SCHEMBL16958767 | 0.78 | GRM5 (0.33) | CYP2A6LOXL2MEN1KMT2A | |
| SCHEMBL458972 | 0.78 | CYP2A6 (0.50) | CYP2A6LOXL2MEN1KMT2A | |
| SCHEMBL6965146 | 0.78 | CYP2A6 (0.31) | CYP2A6LOXL2MEN1KMT2A | |
| SCHEMBL18301559 | 0.77 | KDM4E (0.43) | KDM4ETDP1ENPP2CYP2A6LOXL2 | |
| SCHEMBL501879 | 0.77 | KDM4E (0.43) | KDM4ETDP1ENPP2CYP2A6LOXL2 | |
| SCHEMBL16959862 | 0.76 | TSHR (0.45) | CYP2A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |