Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335656 | 0.82 | LOXL2 (0.35) | CYP2A6LOXL2 | |
| SCHEMBL6958311 | 0.78 | KDM4E (0.34) | CYP2A6MEN1KMT2ALOXL2 | |
| SCHEMBL28049287 | 0.78 | GRM5 (0.31) | CYP2A6LOXL2 | |
| SCHEMBL16958767 | 0.78 | GRM5 (0.33) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL458972 | 0.78 | CYP2A6 (0.50) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL28302773 | 0.78 | LOXL2 (0.50) | CYP2A6LOXL2 | |
| SCHEMBL11609185 | 0.78 | TRPA1 (0.36) | — | |
| SCHEMBL916379 | 0.77 | TTR (0.41) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL14689467 | 0.77 | TTR (0.41) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL27491 | 0.75 | TSHR (0.38) | CYP2A6MEN1TTRALBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |