SCHEMBL501879

SCHEMBL501879

N#CCc1cc(C#N)cc(C#N)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ENPP2 Q13822 1/20 0.36
TTR P02766 2/20 0.36
ALB P02768 2/20 0.36
LOXL2 Q9Y4K0 2/20 0.36
CYP2A6 P11509 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MMP3 P08254 1/20 0.34
VCAM1 P19320 2/20 0.33
FFAR1 O14842 1/20 0.33
TSHR P16473 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18301559 0.95 KDM4E (0.43) KDM4ETDP1ENPP2TTRALB
SCHEMBL1484452 0.84 KDM4E (0.37) KDM4ETDP1ENPP2TTRALB
SCHEMBL501516 0.84 CYP2A6 (0.38) KDM4ETDP1ENPP2TTRALB
SCHEMBL501685 0.84 KDM4E (0.41) KDM4ETDP1VCAM1
SCHEMBL25990556 0.84 KDM4E (0.37) KDM4ETDP1CYP11B1CYP11B2
SCHEMBL4007007 0.80 KDM4E (0.52) KDM4ETDP1ENPP2MEN1KMT2A
SCHEMBL24108532 0.80 RXRA (0.46) KDM4ETDP1MEN1KMT2A
SCHEMBL1542913 0.78 LOXL2 (0.41) TTRALBLOXL2CYP2A6MEN1
SCHEMBL3063453 0.77 ENPP2 (0.53) KDM4ETDP1ENPP2MEN1KMT2A
SCHEMBL6958311 0.77 KDM4E (0.34) KDM4ETDP1ENPP2LOXL2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646086-A2 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG Display Co., Ltd. (KR) 2025-11-05 EP disclosed
EP-4009392-B1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO LTD (KR) 2025-11-05 EP disclosed
WO-2024126528-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE NOVALED GMBH (DE) 2024-06-20 WO disclosed
CN-115677731-B Organic compound and application thereof in organic electronic device 广州追光科技有限公司 2024-04-16 CN disclosed
CN-112390784-B Organic compound, organic light emitting diode including the same, and organic light emitting display device 乐金显示有限公司 2024-02-20 CN disclosed
US-11889754-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD (KR) 2024-01-30 US disclosed
US-11877507-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2024-01-16 US disclosed
US-11877507-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2024-01-16 US disclosed
WO-2023232967-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE NOVALED GMBH (DE) 2023-12-07 WO disclosed
US-20230389415-A1 Organic Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-11-30 US disclosed
EP-3176844-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG Display Co., Ltd. (KR) 2017-06-07 EP disclosed
US-8106064-B2 administering 1-[2-Chloro-6-(4-methoxy-benzylamino)-pyridin-4-ylmethyl]-6-(3-[1,3]dioxolan-2-yl-5-methyl-phenoxy)-5-isopropyl-1H-pyrimidine-2,4-dione viricide to treat AIDS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2012-01-31 US disclosed
US-8106064-B2 administering 1-[2-Chloro-6-(4-methoxy-benzylamino)-pyridin-4-ylmethyl]-6-(3-[1,3]dioxolan-2-yl-5-methyl-phenoxy)-5-isopropyl-1H-pyrimidine-2,4-dione viricide to treat AIDS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2012-01-31 US disclosed
US-20100034827-A1 NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2010-02-11 US disclosed
US-20100034827-A1 NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2010-02-11 US disclosed
EP-2044037-A2 HIV REVERSE TRANSCRIPTASE INHIBITORS Gilead Sciences, Inc. (US) 2009-04-08 EP disclosed
US-20080070920-A1 Novel HIV reverse transcriptase inhibitors KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-03-20 US disclosed
US-20080070920-A1 Novel HIV reverse transcriptase inhibitors KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-03-20 US disclosed
WO-2008016522-A2 HIV REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2008-02-07 WO disclosed
WO-2008016522-A2 HIV REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877507-B2 Organic light emitting display device ALDH1A1, AOX1, ALDH1A2 KDM4E 3706/4885TDP1 1429/4885ENPP2 4082/4885
US-20100034827-A1 NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS POLR2E, POLRMT, POLR2H KDM4E 1269/4885TDP1 143/4885ENPP2 1664/4885
US-11889754-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 KDM4E 3167/4885TDP1 1312/4885ENPP2 2822/4885
US-20080070920-A1 Novel HIV reverse transcriptase inhibitors POLR2E, POLRMT, POLR2H KDM4E 1234/4885TDP1 147/4885ENPP2 1679/4885
US-20230389415-A1 Organic Light Emitting Display Device ALDH1A1, ALDH1A2, OCIAD1 KDM4E 3767/4885TDP1 1287/4885ENPP2 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.