Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080811 | 0.90 | ALDH1A1 (0.42) | POLBALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL6970345 | 0.89 | ALDH1A1 (0.44) | POLBALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL9023589 | 0.89 | L3MBTL1 (0.59) | ALDH1A1L3MBTL1MAPK1TSHRKMT2A | |
| SCHEMBL6972584 | 0.88 | L3MBTL1 (0.43) | POLBALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL6971039 | 0.88 | MEN1 (0.43) | POLBALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL6960634 | 0.85 | KMT2A (0.50) | ALDH1A1L3MBTL1MAPK1MAPTKMT2A | |
| SCHEMBL6961218 | 0.85 | KMT2A (0.50) | ALDH1A1L3MBTL1MAPK1MAPTKMT2A | |
| SCHEMBL6972522 | 0.83 | NPC1 (0.53) | POLBALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9078573 | 0.81 | HSP90AB1 (0.41) | L3MBTL1MAPK1NPSR1LMNAGAA | |
| SCHEMBL9024167 | 0.81 | YWHAG (0.41) | POLBALDH1A1L3MBTL1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |