Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YWHAG | P61981 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972584 | 0.90 | L3MBTL1 (0.43) | YWHAGL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL9080811 | 0.87 | ALDH1A1 (0.42) | L3MBTL1POLBMAPTALDH1A1MEN1 | |
| SCHEMBL6971280 | 0.84 | L3MBTL1 (0.44) | YWHAGL3MBTL1TSHRPOLBLMNA | |
| SCHEMBL6972511 | 0.84 | ALOX5 (0.45) | YWHAGL3MBTL1TSHRALOX5MAPT | |
| SCHEMBL9079669 | 0.83 | CHRNB2 (0.40) | POLBSMN1; SMN2ALDH1A1SLC2A1MEN1 | |
| SCHEMBL6958769 | 0.81 | POLB (0.45) | L3MBTL1TSHRPOLBLMNAGAA | |
| SCHEMBL9027127 | 0.77 | MAPT (0.41) | L3MBTL1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL9080507 | 0.77 | AOC3 (0.45) | LMNAALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL6965330 | 0.77 | ESR1 (0.42) | L3MBTL1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL6974399 | 0.77 | ESR1 (0.42) | L3MBTL1LMNAGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |