Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ERG | P11308 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961546 | 0.90 | KDM4E (0.48) | RBP4KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6962010 | 0.88 | RBP4 (0.57) | RBP4KDM4EALDH1A1HCAR2GAA | |
| SCHEMBL6956583 | 0.87 | KMT2A (0.53) | RBP4KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6961537 | 0.86 | RBP4 (0.54) | RBP4KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6961396 | 0.81 | PANK3 (0.63) | KDM4EALDH1A1HSD17B10POLBHCAR2 | |
| SCHEMBL6960999 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10POLBHCAR2 | |
| SCHEMBL6952726 | 0.81 | MAPT (0.55) | KDM4EALDH1A1POLBGAAKMT2A | |
| SCHEMBL6963652 | 0.80 | HCAR2 (0.44) | RBP4KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL6963644 | 0.80 | KMT2A (0.48) | RBP4ALDH1A1HCAR2KMT2AMAPT | |
| SCHEMBL6963523 | 0.80 | MAPT (0.60) | RBP4KDM4EALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |