Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139732 | 0.88 | RBP4 (0.43) | HCAR2FAAHTRPV1PANK3KMT2A | |
| SCHEMBL6962010 | 0.85 | RBP4 (0.57) | HCAR2FAAHTRPV1PANK3KMT2A | |
| SCHEMBL6961396 | 0.83 | PANK3 (0.63) | HCAR2FAAHTRPV1PANK3KMT2A | |
| SCHEMBL6960999 | 0.83 | KDM4E (0.52) | HCAR2TRPV1PANK3KMT2AMEN1 | |
| SCHEMBL6952726 | 0.82 | MAPT (0.55) | FAAHTRPV1PANK3KMT2AMEN1 | |
| SCHEMBL6963644 | 0.81 | KMT2A (0.48) | HCAR2FAAHTRPV1PANK3KMT2A | |
| SCHEMBL6963523 | 0.81 | MAPT (0.60) | FAAHUSP2RBP4KDM4EALDH1A1 | |
| SCHEMBL6961546 | 0.81 | KDM4E (0.48) | HCAR2FAAHPANK3KMT2AMEN1 | |
| SCHEMBL6958779 | 0.80 | RBP4 (0.49) | HCAR2FAAHPANK3KMT2ARBP4 | |
| SCHEMBL6964324 | 0.79 | MAPT (0.54) | FAAHPANK3RBP4KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |