Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | ERG | P11308 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960999 | 0.89 | KDM4E (0.52) | TRPV1ALDH1A1NPSR1PANK3KMT2A | |
| SCHEMBL6961396 | 0.89 | PANK3 (0.63) | SMN1; SMN2MAPK1TRPV1ALDH1A1NPSR1 | |
| SCHEMBL6952726 | 0.88 | MAPT (0.55) | RAB9ASMN1; SMN2MAPK1TRPV1ALDH1A1 | |
| SCHEMBL6958779 | 0.88 | RBP4 (0.49) | RBP4ALDH1A1FAAHERGSMO | |
| SCHEMBL6963644 | 0.87 | KMT2A (0.48) | RBP4TRPV1ALDH1A1FAAHERG | |
| SCHEMBL6962593 | 0.87 | RBP4 (0.61) | RBP4RAB9ASMN1; SMN2MAPK1TRPV1 | |
| SCHEMBL6963523 | 0.87 | MAPT (0.60) | RBP4RAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL6963652 | 0.85 | HCAR2 (0.44) | RBP4RAB9ATRPV1ALDH1A1FAAH | |
| SCHEMBL6961546 | 0.84 | KDM4E (0.48) | RBP4MAPK1ALDH1A1FAAHHTR1A | |
| SCHEMBL6964324 | 0.82 | MAPT (0.54) | RBP4RAB9AMAPK1FAAHHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |