Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958842 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAGLASMN1; SMN2CSNK1D | |
| SCHEMBL6959035 | 0.88 | SMN1; SMN2 (0.54) | ALDH1A1LMNAGLASMN1; SMN2CSNK1D | |
| SCHEMBL6959039 | 0.88 | SMN1; SMN2 (0.54) | ALDH1A1LMNAGLASMN1; SMN2CSNK1D | |
| SCHEMBL6963473 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAGLASMN1; SMN2MMP1 | |
| SCHEMBL6963475 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAGLASMN1; SMN2MMP1 | |
| SCHEMBL6963338 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAGLASMN1; SMN2MMP1 | |
| SCHEMBL6963333 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAGLASMN1; SMN2MMP1 | |
| SCHEMBL12210179 | 0.81 | TACR3 (0.55) | ALDH1A1LMNASMN1; SMN2CSNK1DNFKB1 | |
| SCHEMBL6949394 | 0.79 | MMP3 (0.82) | ALDH1A1LMNAGLAMMP1MMP3 | |
| SCHEMBL6952333 | 0.78 | PKM (0.57) | ALDH1A1LMNAGLASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |