SCHEMBL6959093

SCHEMBL6959093

CC(C)(Oc1ccc2c(c1)OC(=Cc1ccc3c(c1)OCCO3)C2=O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 19/20 0.62
PPARA Q07869 17/20 0.62
PPARG P37231 11/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6959084 1.00 PPARD (0.62) PPARDPPARAPPARG
SCHEMBL7132653 0.84 MEN1 (0.67)
SCHEMBL6959110 0.83 MAOB (0.73)
SCHEMBL6969899 0.83 MAOB (0.51) PPARDPPARAPPARG
SCHEMBL6954900 0.83 MAOB (0.51) PPARDPPARAPPARG
SCHEMBL6959932 0.82 MAOB (0.55)
SCHEMBL6960544 0.81 MEN1 (0.61)
SCHEMBL6965017 0.80 ACHE (0.60) PPARDPPARAPPARG
SCHEMBL6957011 0.80 MEN1 (0.68)
SCHEMBL23066258 0.79 PPARD (0.79) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0902022-B1 NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME DAIICHI SEIYAKU CO (JP) 2003-07-30 EP disclosed
US-6143779-A Benzofuranone derivatives and a method for producing them SNOW BRAND MILK PRODUCTS CO., LTD. (JP) 2000-11-07 US disclosed
EP-0902022-A1 NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SNOW BRAND MILK PRODUCTS CO., LTD. (JP) 1999-03-17 EP disclosed