Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | KIT | P10721 | 1/20 | 0.60 |
| ▸ | STK17B | O94768 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | BLK | P51451 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.58 |
| ▸ | TEK | Q02763 | 1/20 | 0.58 |
| ▸ | BTK | Q06187 | 1/20 | 0.58 |
| ▸ | ITK | Q08881 | 1/20 | 0.58 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.58 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965017 | 0.87 | ACHE (0.60) | MAOBSTK17BKDM4EMEN1KMT2A | |
| SCHEMBL6959932 | 0.87 | MAOB (0.55) | MAOBPTGS2KITSTK17BRAB9A | |
| SCHEMBL7132653 | 0.87 | MEN1 (0.67) | MAOBPTGS2KITSTK17BRAB9A | |
| SCHEMBL6971491 | 0.85 | PPARG (0.58) | MAOBSTK17B | |
| SCHEMBL6965219 | 0.85 | PPARG (0.61) | MAOB | |
| SCHEMBL6959089 | 0.84 | MEN1 (0.62) | MAOBPTGS2KITSTK17BKDM4E | |
| SCHEMBL6969960 | 0.84 | PNLIP (0.57) | MAOBSTK17B | |
| SCHEMBL6969899 | 0.84 | MAOB (0.51) | MAOBPTGS2KITRAB9AKDM4E | |
| SCHEMBL6960544 | 0.84 | MEN1 (0.61) | MAOBSTK17BRAB9AKDM4EALDH1A1 | |
| SCHEMBL6954900 | 0.84 | MAOB (0.51) | MAOBPTGS2KITRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |