Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | PPARD | Q03181 | 2/20 | 0.59 |
| ▸ | STK17B | O94768 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970149 | 0.93 | MEN1 (0.61) | ACHEPPARGPPARDSTK17BPPARA | |
| SCHEMBL6970155 | 0.93 | MEN1 (0.61) | ACHEPPARGPPARDSTK17BPPARA | |
| SCHEMBL6971491 | 0.91 | PPARG (0.58) | ACHEPPARGPPARDSTK17BPPARA | |
| SCHEMBL6965219 | 0.91 | PPARG (0.61) | ACHEPPARGPPARDPPARAMAOB | |
| SCHEMBL6969960 | 0.89 | PNLIP (0.57) | ACHEPPARGPPARDSTK17BPPARA | |
| SCHEMBL6971306 | 0.89 | PNLIP (0.59) | ACHEPPARGPPARDSTK17BPPARA | |
| SCHEMBL6959110 | 0.87 | MAOB (0.73) | STK17BMAOBMEN1KMT2AKDM4E | |
| SCHEMBL6960544 | 0.85 | MEN1 (0.61) | ACHESTK17BMAOBMEN1KMT2A | |
| SCHEMBL6962114 | 0.85 | PPARG (0.61) | ACHEPPARGPPARDPPARAMAOB | |
| SCHEMBL6968934 | 0.85 | MEN1 (0.59) | ACHEPPARGPPARDSTK17BPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |