Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053132 | 0.78 | CA2 (0.59) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6959197 | 0.78 | CA2 (0.46) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6971647 | 0.77 | CA2 (0.50) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL517957 | 0.76 | TAS2R38 (0.46) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL18160927 | 0.73 | CA2 (0.53) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL2833779 | 0.73 | CA2 (0.53) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6971654 | 0.71 | CA2 (0.50) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL25756850 | 0.71 | CA2 (0.50) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6972226 | 0.69 | CA2 (0.48) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL8589178 | 0.69 | CA2 (0.48) | CA2ALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |