Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959311 | 1.00 | KDM4E (0.45) | KDM4ELMNANCOA1NCOA3ABCG2 | |
| SCHEMBL4384277 | 0.81 | ALDH1A1 (0.64) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6956520 | 0.81 | ALDH1A1 (0.64) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6960216 | 0.79 | KMT2A (0.61) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2636596 | 0.77 | KMT2A (0.49) | KDM4ELMNAABCG2MEN1KMT2A | |
| SCHEMBL6949727 | 0.77 | KMT2A (0.49) | KDM4ELMNAABCG2MEN1KMT2A | |
| SCHEMBL29383650 | 0.77 | KMT2A (0.49) | KDM4ELMNAABCG2MEN1KMT2A | |
| SCHEMBL6960507 | 0.76 | PLA2G2A (0.55) | KDM4ELMNAABCG2MEN1KMT2A | |
| SCHEMBL10746185 | 0.75 | ALDH1A1 (0.70) | KDM4ELMNAABCG2MEN1KMT2A | |
| SCHEMBL10566353 | 0.74 | ALDH1A1 (0.44) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | claimed |