Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568350 | 0.90 | XDH (0.48) | ALDH1A1HTTPRSS1MEN1NPC1 | |
| SCHEMBL10566344 | 0.82 | RAB9A (0.41) | ALDH1A1HTTKDM4EMEN1NPC1 | |
| SCHEMBL6959311 | 0.74 | KDM4E (0.45) | ALDH1A1HTTKDM4EMEN1MAPK1 | |
| SCHEMBL6959324 | 0.74 | KDM4E (0.45) | ALDH1A1HTTKDM4EMEN1MAPK1 | |
| SCHEMBL10567349 | 0.72 | ADORA3 (0.52) | ALDH1A1KDM4EMEN1POLBNFKB1 | |
| SCHEMBL10568361 | 0.71 | PTGDR2 (0.42) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10568339 | 0.71 | PTGDR2 (0.42) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10746185 | 0.71 | ALDH1A1 (0.70) | ALDH1A1HTTKDM4EMEN1NPC1 | |
| SCHEMBL11420458 | 0.71 | HTT (0.52) | ALDH1A1HTTPRSS1MEN1POLB | |
| SCHEMBL27804692 | 0.71 | KMT2A (0.55) | ALDH1A1PRSS1KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843085-A | LOCAL ANESTHETICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0297613-A2 | Pyridine derivatives, process for production thereof and pharmaceutical composition containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |