Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955473 | 0.91 | ALOX5 (0.46) | ALOX5SMN1; SMN2MAPTLMNALTA4H | |
| SCHEMBL6963479 | 0.88 | ALOX5 (0.45) | ALOX5SMN1; SMN2MAPTEGFRNPC1 | |
| SCHEMBL6963529 | 0.86 | ALOX5 (0.44) | ALOX5SMN1; SMN2MAPTLMNAEGFR | |
| SCHEMBL6964844 | 0.85 | ALOX5 (0.50) | ALOX5SMN1; SMN2MAPTLTA4HEPHX2 | |
| SCHEMBL6961755 | 0.85 | ALOX5 (0.52) | ALOX5SMN1; SMN2MAPTLTA4HEPHX2 | |
| SCHEMBL6953893 | 0.82 | ALOX5 (0.48) | ALOX5SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL8685472 | 0.81 | ALOX5 (0.46) | ALOX5SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL6959060 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2MAPTLMNAALDH1A1HPGD | |
| SCHEMBL6954427 | 0.80 | ALOX5 (0.44) | ALOX5MAPTLMNANPC1RAB9A | |
| SCHEMBL6962860 | 0.79 | ALOX5 (0.52) | ALOX5SMN1; SMN2MAPTLTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |