Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963453 | 0.94 | ALOX5 (0.49) | ALOX5PTGS2GLO1ALDH1A1POLB | |
| SCHEMBL6963479 | 0.91 | ALOX5 (0.45) | ALOX5ALDH1A1KDM4EPKMKMT2A | |
| SCHEMBL6961755 | 0.91 | ALOX5 (0.52) | ALOX5ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL6954427 | 0.91 | ALOX5 (0.44) | ALOX5GLO1ALDH1A1POLBLMNA | |
| SCHEMBL6955473 | 0.86 | ALOX5 (0.46) | ALOX5PTGS2GLO1ALDH1A1POLB | |
| SCHEMBL6955391 | 0.86 | RAB9A (0.53) | ALOX5ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL6962415 | 0.86 | MTNR1A (0.50) | ALOX5PTGS2GLO1ALDH1A1POLB | |
| SCHEMBL6963529 | 0.84 | ALOX5 (0.44) | ALOX5ALDH1A1LMNAKDM4EPKM | |
| SCHEMBL6964844 | 0.83 | ALOX5 (0.50) | ALOX5ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL6962860 | 0.83 | ALOX5 (0.52) | ALOX5ALDH1A1POLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |