Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089043 | 0.85 | ALDH1A1 (0.52) | LMNASMN1; SMN2ALDH1A1GAATDP1 | |
| SCHEMBL19311886 | 0.78 | ALDH1A1 (0.44) | LMNASMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL19927626 | 0.78 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1GAATDP1 | |
| SCHEMBL10341213 | 0.78 | PKM (0.55) | LMNASMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL30180164 | 0.78 | PKM (0.55) | LMNASMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL14993397 | 0.78 | PKM (0.51) | LMNASMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL18159268 | 0.77 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1GAACYP3A4 | |
| SCHEMBL2955974 | 0.77 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL29738113 | 0.77 | ALDH1A1 (0.50) | LMNASMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL6370714 | 0.77 | ALDH1A1 (0.50) | LMNASMN1; SMN2ALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |