Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766900 | 0.98 | EPHX1 (0.34) | EPHX1HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL11070169 | 0.77 | HTT (0.42) | EPHX1HTTNPC1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27548538 | 0.76 | HTT (0.41) | EPHX1HTTNPC1GAASMN1; SMN2 | |
| Acetic Acid SCHEMBL28202127 | 0.71 | EPHX1 (0.36) | EPHX1HTTCES2CES1CA1 | |
| SCHEMBL9639066 | 0.70 | EPHX1 (0.35) | EPHX1HTTCES2CES1LMNA | |
| Bicarbonate SCHEMBL366336 | 0.69 | EPHX1 (0.43) | EPHX1HTTNPC1SMN1; SMN2FABP7 | |
| Bicarbonate SCHEMBL6566447 | 0.69 | EPHX1 (0.43) | EPHX1HTTNPC1SMN1; SMN2FABP7 | |
| Bicarbonate SCHEMBL28775658 | 0.69 | EPHX1 (0.43) | EPHX1HTTNPC1SMN1; SMN2FABP7 | |
| SCHEMBL9432 | 0.69 | — | — | |
| SCHEMBL93205 | 0.69 | CA1 (0.39) | EPHX1NPC1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687911-A | Cysteine derivatives of antiviral peptides | CONJUCHEM BIOTECHNOLOGIES INC | 2010-03-31 | — | — | CN | disclosed |
| CN-101663317-A | Glucagon-like protein-1 receptor GLP-1R agonist compounds | COVX TECHNOLOGIES IRELAND LTD | 2010-03-03 | — | — | CN | disclosed |
| CN-1247582-C | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMACEUTI (JP) | 2006-03-29 | — | — | CN | disclosed |
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1489589-A | Novel carbapenem compounds | ס����ҩ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| CN-1129428-C | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2003-12-03 | — | — | CN | disclosed |
| EP-0699069-B9 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-0699069-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-02-13 | — | — | EP | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |
| CN-1124923-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1996-06-19 | — | — | CN | disclosed |
| EP-0699069-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0699069-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994025013-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-10 | — | — | WO | disclosed |