Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952759 | 0.85 | NPSR1 (0.67) | GAAALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL9453905 | 0.81 | MAPT (0.79) | GAAALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL6961905 | 0.79 | GAA (0.62) | GAAALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL6959673 | 0.77 | ALDH1A1 (0.60) | GAAALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL18311282 | 0.75 | KMT2A (0.60) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6957744 | 0.74 | ALDH1A1 (0.56) | GAAALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL6905305 | 0.74 | GAA (0.56) | GAAALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL23264324 | 0.73 | ALDH1A1 (0.68) | GAAALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL6955646 | 0.73 | ALDH1A1 (0.68) | GAAALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL6900443 | 0.73 | GAA (0.55) | GAAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |