Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.62 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954502 | 0.84 | GPR119 (0.61) | GPR119CETPALKCHEK2ALDH1A1 | |
| SCHEMBL6961126 | 0.82 | GPR119 (0.58) | GPR119ALKCHEK2 | |
| SCHEMBL225375 | 0.81 | GPR119 (0.91) | GPR119ALK | |
| SCHEMBL8476721 | 0.81 | GPR119 (0.50) | GPR119CETPALK | |
| SCHEMBL6959761 | 0.79 | GPR119 (0.54) | GPR119CETPALKCHEK2 | |
| SCHEMBL3340944 | 0.78 | GPR119 (0.85) | GPR119ALKCHEK2PTPN2PTPN1 | |
| SCHEMBL8469775 | 0.78 | GPR119 (0.60) | GPR119CETPALKCHEK2 | |
| SCHEMBL8115238 | 0.78 | GPR119 (0.59) | GPR119CETPALKPTPN2PTPN1 | |
| SCHEMBL8114017 | 0.77 | GPR119 (0.59) | GPR119CETPALKPTPN2PTPN1 | |
| SCHEMBL2573355 | 0.77 | GPR119 (1.00) | GPR119ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798295-B1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-5869501-A | PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS OR EMBOLUS. | YAMANOUCHI PHARMACEUTICAL CO. LTD (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |