Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.59 |
| ▸ | CETP | P11597 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114017 | 0.87 | GPR119 (0.59) | GPR119CETPALKPTPN2PTPN1 | |
| SCHEMBL8113514 | 0.87 | GPR119 (0.58) | GPR119CETPALDH1A1MAPTALK | |
| SCHEMBL8104569 | 0.86 | ALDH1A1 (0.49) | GPR119ALDH1A1MAPTNPC1NFKB1 | |
| SCHEMBL8120896 | 0.83 | GPR119 (0.52) | GPR119CETPALDH1A1ALK | |
| SCHEMBL5971141 | 0.82 | GPR119 (0.57) | GPR119CETPALDH1A1ALKPTPN2 | |
| SCHEMBL5971135 | 0.82 | GPR119 (0.57) | GPR119CETPALDH1A1ALKPTPN2 | |
| SCHEMBL3895250 | 0.82 | GPR119 (0.58) | GPR119CETPALK | |
| SCHEMBL8120146 | 0.82 | GPR119 (0.52) | GPR119CETPALK | |
| SCHEMBL8121326 | 0.81 | GPR119 (0.51) | GPR119CETPALK | |
| SCHEMBL3605978 | 0.81 | GPR119 (0.69) | GPR119ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |