Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.59 |
| ▸ | CETP | P11597 | 8/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113514 | 0.91 | GPR119 (0.58) | GPR119CETPALKPTPN2PTPN1 | |
| SCHEMBL8115238 | 0.87 | GPR119 (0.59) | GPR119CETPALKPTPN2PTPN1 | |
| SCHEMBL8120146 | 0.86 | GPR119 (0.52) | GPR119CETPALK | |
| SCHEMBL8120896 | 0.86 | GPR119 (0.52) | GPR119CETPALK | |
| SCHEMBL6188104 | 0.81 | GPR119 (0.57) | GPR119CETPALK | |
| SCHEMBL225375 | 0.79 | GPR119 (0.91) | GPR119ALK | |
| SCHEMBL31716198 | 0.79 | TGFBR1 (0.51) | GPR119CETP | |
| SCHEMBL6192221 | 0.78 | GPR119 (0.61) | GPR119CETPALK | |
| SCHEMBL6959826 | 0.77 | GPR119 (0.62) | GPR119CETPALKPTPN2PTPN1 | |
| SCHEMBL6954502 | 0.77 | GPR119 (0.61) | GPR119CETPALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |