Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184770 | 0.84 | HCAR2 (0.39) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL14392455 | 0.84 | HCAR2 (0.39) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL31446649 | 0.84 | HCAR2 (0.39) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL5488826 | 0.84 | HCAR2 (0.39) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL31368733 | 0.84 | HCAR2 (0.39) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL24808960 | 0.84 | KDM4E (0.42) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL16135687 | 0.84 | HCAR2 (0.39) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15645118 | 0.83 | HCAR2 (0.38) | HCAR2KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL30064557 | 0.81 | ASPH (0.40) | HCAR2KDM4EASPHKDM8 | |
| SCHEMBL17125870 | 0.81 | ASPH (0.40) | HCAR2KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930884-A | Fluorine-containing metal organic framework material for methane and nitrogen separation, and preparation method and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | claimed |
| CN-116936810-B | Positive pole piece of sodium ion battery and sodium ion battery | 天鹏锂能技术(淮安)有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-116936810-A | Positive pole piece of sodium ion battery and sodium ion battery | 天鹏锂能技术(淮安)有限公司 | 2023-10-24 | — | — | CN | claimed |
| US-12281057-B2 | Carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-04-22 | — | — | US | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025054260-A1 | INHIBITORS OF MEK KINASE | KINNATE BIOPHARMA INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-119176794-A | Heterocyclic compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| EP-3651752-B1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-118930884-A | Fluorine-containing metal organic framework material for methane and nitrogen separation, and preparation method and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | disclosed |
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
| US-20240174696-A1 | 2,8-DIAZASPIRO[4.5]DECANE COMPOUNDS | GENENTECH, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| EP-2421835-A1 | N-PYRAZOLYL CARBOXAMIDES AS CRAC CHANNEL INHIBITORS | Glaxo Group Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| WO-2011139765-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011139489-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110263612-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2010142752-A1 | JANUS KINASE INHIBITOR COMPOUNDS AND METHODS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |
| US-20100317643-A1 | JANUS KINASE INHIBITOR COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2010-12-16 | — | — | US | disclosed |
| WO-2010122089-A1 | N-PYRAZOLYL CARBOXAMIDES AS CRAC CHANNEL INHIBITORS | GLAXO GROUP LIMITED (GB) | 2010-10-28 | — | — | WO | disclosed |
| US-20100273744-A1 | COMPOUNDS | GORE PAUL MARTIN | 2010-10-28 | — | — | US | disclosed |
| WO-2006083477-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174696-A1 | 2,8-DIAZASPIRO[4.5]DECANE COMPOUNDS | LATS1, LATS2, GLS2 | HCAR2 1433/4885KDM4E 1411/4885ASPH 2673/4885 |
| US-20240279215-A1 | NAMPT MODULATORS | NAMPT, SIRT1, NNT | HCAR2 667/4885KDM4E 1782/4885ASPH 2685/4885 |
| US-20100317643-A1 | JANUS KINASE INHIBITOR COMPOUNDS AND METHODS | JAK2, JAK1, JAK3 | HCAR2 1876/4885KDM4E 572/4885ASPH 1462/4885 |
| US-20110263612-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | HCAR2 343/4885KDM4E 4057/4885ASPH 4523/4885 |
| US-20100273744-A1 | COMPOUNDS | LTC4S, HRH4, HRH2 | HCAR2 94/4885KDM4E 1410/4885ASPH 469/4885 |
| US-12281057-B2 | Carboxamides as modulators of sodium channels | TRPV1, SCN2A, SCN10A | HCAR2 207/4885KDM4E 1582/4885ASPH 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.