⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959854 | 1.00 | — | — | |
| SCHEMBL3226453 | 0.72 | — | — | |
| SCHEMBL424752 | 0.69 | — | — | |
| SCHEMBL10060050 | 0.69 | — | — | |
| SCHEMBL2755012 | 0.63 | — | — | |
| SCHEMBL422028 | 0.62 | POLB (0.32) | — | |
| SCHEMBL8546879 | 0.62 | — | — | |
| SCHEMBL7982091 | 0.55 | MAPT (0.41) | — | |
| SCHEMBL7982094 | 0.55 | MAPT (0.41) | — | |
| SCHEMBL3226313 | 0.55 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850231-B1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-02 | — | — | EP | claimed |
| US-6187927-B1 | REACTING 2-CHLOROALLYLFORMAMIDE WITH DEHYDRATING, HALOGENATING, AND SULFURIZING AGENTS | NOVARTIS CROP PROTECTION, INC. | 2001-02-13 | — | — | US | claimed |
| EP-0850231-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | Novartis AG (CH) | 1998-07-01 | — | — | EP | claimed |
| WO-1997010226-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | NOVARTIS AG (CH) | 1997-03-20 | — | — | WO | claimed |
| EP-0850231-B1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-02 | — | — | EP | disclosed |
| EP-0850231-B1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-02 | — | — | EP | disclosed |
| US-6187927-B1 | REACTING 2-CHLOROALLYLFORMAMIDE WITH DEHYDRATING, HALOGENATING, AND SULFURIZING AGENTS | NOVARTIS CROP PROTECTION, INC. | 2001-02-13 | — | — | US | disclosed |
| US-6187927-B1 | REACTING 2-CHLOROALLYLFORMAMIDE WITH DEHYDRATING, HALOGENATING, AND SULFURIZING AGENTS | NOVARTIS CROP PROTECTION, INC. | 2001-02-13 | — | — | US | disclosed |
| EP-0850231-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | Novartis AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| EP-0850231-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | Novartis AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997010226-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | NOVARTIS AG (CH) | 1997-03-20 | — | — | WO | disclosed |
| WO-1997010226-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | NOVARTIS AG (CH) | 1997-03-20 | — | — | WO | disclosed |