Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982091 | 1.00 | MAPT (0.41) | MAPTHTTCHRNB2CHRNA4 | |
| SCHEMBL3226313 | 1.00 | MAPT (0.41) | MAPTHTTCHRNB2CHRNA4 | |
| SCHEMBL11348502 | 0.89 | CHRNB2 (0.35) | MAPTHTTCHRNB2CHRNA4 | |
| SCHEMBL11348506 | 0.89 | CHRNB2 (0.35) | MAPTHTTCHRNB2CHRNA4 | |
| SCHEMBL7999647 | 0.77 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL2755013 | 0.77 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL7999644 | 0.77 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL10580540 | 0.75 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL10580544 | 0.75 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL2042132 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170112132-A1 | PESTICIDAL MIXTURES INCLUDING SPIROHETEROCYCLIC PYRROLIDINE DIONES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-04-27 | — | — | US | disclosed |
| US-20170071203-A1 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| US-9560851-B2 | Pesticidal mixtures including spiroheterocyclic pyrrolidine diones | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-07 | — | — | US | disclosed |
| US-6297374-B1 | Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-02 | — | — | US | disclosed |
| US-6022967-A | 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0500952-B1 | PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLE | NIPPON SODA CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5750704-A | INSECTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5580889-A | Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-03 | — | — | US | disclosed |
| US-5461167-A | 2-chloro-5-chloromethyl thiazole; insecticide | NIHON BAYER AGROCHEM K.K. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5453529-A | Nitroimino compound as intermediate for insecticides and pharmaceuticals | NIPPON SODA CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |
| US-5428032-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0500952-A1 | PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLE | NIPPON SODA CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170071203-A1 | Active compound combinations having insecticidal properties | ACHE, BCHE, DDT | MAPT 2386/4885HTT 3921/4885CHRNB2 1194/4885 |
| US-20170112132-A1 | PESTICIDAL MIXTURES INCLUDING SPIROHETEROCYCLIC PYRROLIDINE DIONES | DDT, ECH1, PLD1 | MAPT 4740/4885HTT 3241/4885CHRNB2 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.