SCHEMBL3226313

SCHEMBL3226313

CN1CCN/C1=N\[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7982091 1.00 MAPT (0.41) MAPTHTTCHRNB2CHRNA4
SCHEMBL7982094 1.00 MAPT (0.41) MAPTHTTCHRNB2CHRNA4
SCHEMBL11348502 0.89 CHRNB2 (0.35) MAPTHTTCHRNB2CHRNA4
SCHEMBL11348506 0.89 CHRNB2 (0.35) MAPTHTTCHRNB2CHRNA4
SCHEMBL7999647 0.77 CHRNB2 (0.34) CHRNB2CHRNA4
SCHEMBL2755013 0.77 CHRNB2 (0.34) CHRNB2CHRNA4
SCHEMBL7999644 0.77 CHRNB2 (0.34) CHRNB2CHRNA4
SCHEMBL10580540 0.75 CHRNB2 (0.34) CHRNB2CHRNA4
SCHEMBL10580544 0.75 CHRNB2 (0.34) CHRNB2CHRNA4
SCHEMBL2042132 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9662309-B2 Anti-demodicosis agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-05-30 US disclosed
US-8993483-B2 Combination of active substances with insecticidal properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-03-31 US disclosed
US-8841294-B2 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-8728507-B2 Non-systemic control of parasites BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-20 US disclosed
US-8426339-B2 Method of minimizing herbicidal injury BAYER CROPSCIENCE LP (US) 2013-04-23 US disclosed
US-8410021-B2 Compositions for the control of plant pests BAYER CROPSCIENCE AG (DE) 2013-04-02 US disclosed
US-20130005571-A1 METHOD OF MINIMIZING HERBICIDAL INJURY BAYER CROPSCIENCE LP (US) 2013-01-03 US disclosed
US-8293733-B2 Oil dispersions of nAChR binding neonicotinoids GAT MICROENCAPSULATION AG (AT) 2012-10-23 US disclosed
US-8268750-B2 Combination of active substances with insecticidal properties BAYER CROPSCIENCE AG (DE) 2012-09-18 US disclosed
US-8232261-B2 Pretreatment of plants with insecticides BAYER CROPSCIENCE LP (US) 2012-07-31 US disclosed
US-20100168090-A1 Active Ingredient Combinations With Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AG (DE) 2010-07-01 US disclosed
US-20100041659-A1 Compositions for the control of plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-02-18 US disclosed
US-7659228-B2 Synergistic insecticide mixtures BAYER AKTIENGESELLSCHAFT (DE) 2010-02-09 US disclosed
US-20090325807-A1 Method of Improving Plant Growth BAYER CROPSCIENCE AG (DE) 2009-12-31 US disclosed
US-7384938-B2 Aqueous formulations of parasiticides for skin applications BAYER AKTIENGESELLSCHAFT (DE) 2008-06-10 US disclosed
US-20080090728-A1 Method for Improving Plant Growth BAYER CROPSCIENCE AG (DE) 2008-04-17 US disclosed
US-20080039519-A1 Anti-Demodicosis Agent BAYER HEALTHCARE AG (DE) 2008-02-14 US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 US disclosed
US-20070157507-A1 Method of controlling termites BAYER CROPSCIENCE LP 2007-07-12 US disclosed
US-7214701-B2 Active substance combinations having insecticidal and acaricdal properties BAYER CROPSCIENCE AG (DE) 2007-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041659-A1 Compositions for the control of plant pests RDX, PRXL2A, ACHE MAPT 3102/4885HTT 2674/4885CHRNB2 2879/4885
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties ACHE, CHRM3, CHRNA2 MAPT 3098/4885HTT 2386/4885CHRNB2 16/4885
US-20130005571-A1 METHOD OF MINIMIZING HERBICIDAL INJURY DDT, CBR3, AOX1 MAPT 4464/4885HTT 1641/4885CHRNB2 2207/4885
US-20080039519-A1 Anti-Demodicosis Agent ACHE, DDT, CYP51A1 MAPT 337/4885HTT 57/4885CHRNB2 703/4885
US-20080090728-A1 Method for Improving Plant Growth CHRM3, CHRM2, CHRM5 MAPT 4250/4885HTT 4666/4885CHRNB2 13/4885
US-20090325807-A1 Method of Improving Plant Growth CHRM2, CHRM3, CHRNA1 MAPT 3284/4885HTT 4458/4885CHRNB2 28/4885
US-20100168090-A1 Active Ingredient Combinations With Insecticidal and Acaricidal Properties ACHE, CHRNA2, CHRNA7 MAPT 2330/4885HTT 3371/4885CHRNB2 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.