Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356885 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8355466 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL23038474 | 0.82 | TMEM97 (0.51) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL378609 | 0.82 | MAPT (0.57) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8356716 | 0.80 | MAPT (0.51) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6990807 | 0.80 | MAPT (0.62) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL15569388 | 0.80 | MAPT (0.62) | ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8552607 | 0.79 | BCHE (0.35) | ALDH1A1MAPTKMT2AHTR1ADRD2 | |
| SCHEMBL28776698 | 0.78 | MAPT (0.55) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4172495 | 0.77 | MAPT (0.58) | ALDH1A1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865445-B1 | 3-AMINOETHYL-N-AMIDINO-2,5-DIHYDROPYRROLE DERIVATIVES HAVING ARGININE MIMETIC PROPERTIES | AKZO NOBEL NV (NL) | 2003-04-02 | — | — | EP | disclosed |
| US-20020026034-A1 | 3-AMINOETHYL-N-AMIDINO-2,5-DIHYDROPYRROLE DERIVATIVES HAVING ARGININE MIMETIC PROPERTIES | BOEHRINGER MANNHEIM GMBH (DE) | 2002-02-28 | — | — | US | disclosed |
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5856309-A | TREATING OSTEOPOROSIS, INFLAMMATION OR A DISEASE WHICH IS DUE TO A THROMBOEMBOLIC EVENT | BOEHRINGER MANNHEIM GMBH (DE) | 1999-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026034-A1 | 3-AMINOETHYL-N-AMIDINO-2,5-DIHYDROPYRROLE DERIVATIVES HAVING ARGININE MIMETIC PROPERTIES | ARG1, ODC1, ARG2 | ALDH1A1 1378/4885MAPT 2092/4885KMT2A 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.