Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956640 | 0.85 | L3MBTL1 (0.39) | MAPTSMN1; SMN2L3MBTL1ALDH1A1TP53 | |
| SCHEMBL6962159 | 0.83 | L3MBTL1 (0.40) | MAPTSMN1; SMN2L3MBTL1ALDH1A1TP53 | |
| SCHEMBL8594445 | 0.83 | GRM1 (0.37) | MAPTSMN1; SMN2ALDH1A1GRM1GAA | |
| SCHEMBL6966654 | 0.81 | ALDH1A1 (0.43) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6956204 | 0.81 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL6960156 | 0.76 | ALDH1A1 (0.32) | MAPTSMN1; SMN2ALDH1A1RAB9AGAA | |
| SCHEMBL6956521 | 0.76 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1ALDH1A1TP53 | |
| SCHEMBL6561300 | 0.74 | GAA (0.39) | MAPTSMN1; SMN2L3MBTL1ALDH1A1GAA | |
| SCHEMBL6953240 | 0.72 | KMT2A (0.46) | MAPTSMN1; SMN2ALDH1A1IDO1NPC1 | |
| SCHEMBL8088990 | 0.72 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |