Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130755 | 0.86 | CES2 (0.58) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9502855 | 0.86 | CES2 (0.58) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30179515 | 0.85 | CES2 (0.56) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11169142 | 0.85 | CES2 (0.56) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23037541 | 0.83 | CES2 (0.55) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6960199 | 0.83 | KDM4E (0.55) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11459254 | 0.81 | CES2 (0.59) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5341177 | 0.80 | CES2 (0.63) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6750268 | 0.80 | SMN1; SMN2 (0.65) | CES2POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL503450 | 0.79 | CES2 (0.66) | CES2POLBMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |