Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954964 | 0.77 | MAOB (0.48) | MAOBHPGDS | |
| SCHEMBL15446292 | 0.77 | KDM4E (0.49) | — | |
| SCHEMBL6965085 | 0.76 | KDR (0.53) | — | |
| SCHEMBL6964309 | 0.74 | MAOB (0.51) | MAOBMAOALNPEPPLK1SPHK2 | |
| SCHEMBL6960868 | 0.73 | MAOB (0.52) | MAOBPTPN1HPGDS | |
| SCHEMBL8825070 | 0.72 | MAOB (0.47) | MAOBMAOAALOX5APLNPEPADAMTS4 | |
| SCHEMBL6955421 | 0.72 | FFAR1 (0.47) | — | |
| SCHEMBL6952896 | 0.72 | ALDH1A1 (0.49) | MAOBMAOALNPEP | |
| SCHEMBL8824959 | 0.70 | TDP1 (0.41) | MAOBMAOAALOX5APPLK1 | |
| SCHEMBL6963053 | 0.69 | MAOB (0.43) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1071333-C | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1170411-A | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |