Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 12/20 | 0.50 |
| ▸ | PPARA | Q07869 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157011 | 0.78 | PPARG (0.72) | PPARGPPARA | |
| SCHEMBL6584575 | 0.78 | FFAR1 (0.49) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL29691546 | 0.77 | FFAR1 (0.70) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL6963034 | 0.77 | KDR (0.57) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL7559600 | 0.76 | KDR (0.83) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL6971980 | 0.76 | FFAR1 (0.47) | KDRFFAR1PPARGPPARAMAPT | |
| SCHEMBL8126485 | 0.76 | PPARG (0.74) | PPARGPPARA | |
| SCHEMBL6960726 | 0.76 | KDR (0.50) | KDRFFAR1PPARGPPARA | |
| SCHEMBL6960411 | 0.76 | MAOB (0.45) | — | |
| SCHEMBL6967037 | 0.75 | KDR (0.53) | KDRFFAR1PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |