Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | HTR1D | P28221 | 3/20 | 0.58 |
| ▸ | HTR1B | P28222 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962601 | 0.89 | RBP4 (0.57) | RBP4HTR1AHTR1DHTR1BPOLB | |
| SCHEMBL6959670 | 0.89 | RBP4 (0.69) | RBP4POLBUSP2HSD17B10LMNA | |
| SCHEMBL6966493 | 0.88 | RBP4 (0.56) | RBP4HTR1AHTR1DHTR1BPOLB | |
| SCHEMBL6960558 | 0.87 | MAPT (0.67) | RBP4HTR1AHTR1DHTR1BLMNA | |
| SCHEMBL6960605 | 0.86 | RBP4 (0.54) | RBP4HTR1AHTR1DHTR1BPOLB | |
| SCHEMBL6956210 | 0.86 | GAA (0.57) | RBP4HTR1AHTR1DHTR1BPOLB | |
| SCHEMBL6780561 | 0.85 | MEN1 (0.73) | POLBLMNAKMT2AGAAMAPT | |
| SCHEMBL6965400 | 0.85 | RBP4 (0.60) | RBP4HTR1AHTR1DHTR1BLMNA | |
| SCHEMBL6967002 | 0.85 | RBP4 (0.76) | RBP4HTR1AHTR1DHTR1BPOLB | |
| SCHEMBL6966587 | 0.84 | RBP4 (0.52) | RBP4HTR1AHTR1DHTR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |