Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | HTR1D | P28221 | 5/20 | 0.54 |
| ▸ | HTR1B | P28222 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960558 | 0.91 | MAPT (0.67) | RBP4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL6967002 | 0.89 | RBP4 (0.76) | RBP4KMT2AMAPTRAB9AHTR1A | |
| SCHEMBL6960101 | 0.87 | MAPT (0.59) | RBP4MAPTRAB9AHTR1AHTR1D | |
| SCHEMBL6965687 | 0.86 | RBP4 (0.57) | RBP4KMT2AMAPTRAB9AHTR1A | |
| SCHEMBL6962308 | 0.85 | RBP4 (0.56) | RBP4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL6960722 | 0.85 | RBP4 (0.71) | RBP4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL6965639 | 0.84 | RBP4 (0.55) | RBP4KMT2AMAPTRAB9AHTR1A | |
| SCHEMBL6961204 | 0.83 | HTR1A (0.62) | RBP4MAPTRAB9AHTR1AHTR1D | |
| SCHEMBL3442215 | 0.83 | HTR1A (0.61) | RBP4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL6959675 | 0.82 | THRB (0.53) | RBP4KMT2AMAPTRAB9AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |