Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 6/20 | 0.76 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | HTR1D | P28221 | 3/20 | 0.62 |
| ▸ | HTR1B | P28222 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960558 | 0.91 | MAPT (0.67) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6965400 | 0.89 | RBP4 (0.60) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6960101 | 0.87 | MAPT (0.59) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6956652 | 0.86 | KMT2A (0.61) | RBP4GAAMAPTRAB9AKMT2A | |
| SCHEMBL16690804 | 0.86 | RBP4 (1.00) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6965687 | 0.86 | RBP4 (0.57) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6962308 | 0.85 | RBP4 (0.56) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6960722 | 0.85 | RBP4 (0.71) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6965639 | 0.84 | RBP4 (0.55) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6959670 | 0.83 | RBP4 (0.69) | RBP4GAAMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |