Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.87 |
| ▸ | MMP3 | P08254 | 7/20 | 0.87 |
| ▸ | MMP1 | P03956 | 2/20 | 0.87 |
| ▸ | MMP9 | P14780 | 2/20 | 0.87 |
| ▸ | MMP14 | P50281 | 2/20 | 0.87 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965286 | 0.93 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6584994 | 0.91 | MMP2 (0.85) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6435131 | 0.91 | MMP2 (0.72) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6436932 | 0.91 | MMP2 (0.71) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6435723 | 0.86 | MMP2 (0.84) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586804 | 0.84 | MMP3 (1.00) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6972569 | 0.84 | MMP2 (0.84) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586527 | 0.84 | MMP2 (0.71) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6433680 | 0.83 | MMP2 (0.82) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6588355 | 0.82 | MMP2 (0.70) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |